de Mamiel
de Mamiel was created by skincare expert Annee de Mamiel, who has over 15 years of holistic beauty experience at her aesthetic clinics in London, New York and Los Angeles.
Designed to deeply treat the impact of stress on the skin, de Mamiel offers clean beauty products with professional effectiveness. Harnessing unique plant extracts, biotechnological active ingredients and rare essential oils, its potent skincare formulas visibly transform the skin and restore its total equilibrium.
de Mamiel's unique multidisciplinary approach combines advanced Western scientific research, traditional Chinese medicine and ancient holistic practices to stimulate the skin's innate ability to self-repair while neutralizing the impact of environmental stressors.
Based on the unique clinical expertise of de Mamiel, this line of natural high-performance skincare products optimizes the skin and instills a deeper sense of well-being.


















A potent bio-active serum which targets the specific stress response of Glycation, which occurs when long-term elevated cortisol produces excess glucose resulting in wrinkles, sagginess, dullness and a weakened barrier function.
Know moreWhy we love de Mamiel ?
- Its holistic approach unites science and soul to build better skin
- Its clinical skincare products engineered for transformative results
- Its expert routine that addresses the root causes and treat the impact of stress on the skin
The DE MAMIEL Brand
Created by celebrated skin health expert Annee de Mamiel, this eponymous brand offers a collection of scientifically crafted, natural formulas designed to counteract the visible effects of stress on the skin.
Each product is hand-blended in Annee’s countryside lab in the UK and reflects her deep clinical expertise and holistic approach to skincare and wellbeing.
About De Mamiel
With degrees in anatomy, physiology, acupuncture, and oriental aromatherapy, Annee de Mamiel bridges the gap between Western science and traditional Eastern medicine. Her method? Tackling the root causes of stress while soothing the symptoms, restoring skin and mind to a balanced, radiant state.
At the core of her philosophy is the idea that even the smallest daily gestures—like cleansing your face—can become transformative rituals. Her "Rituals to Results" mantra invites us to slow down, breathe, and bring intention into our beauty routines, turning self-care into soul care.
Annee de Mamiel, founder of DE MAMIEL Skincare
The DE MAMIEL Philosophy
The De Mamiel lineThe skin is a living canvas—an instant stress barometer that mirrors the emotional, physical and cellular strain we experience daily. That’s why each De Mamiel formula is rooted in the brand’s unique EPiC method, a three-pronged approach to managing stress holistically.
In a world obsessed with fast fixes, De Mamiel is a breath of fresh air. This brand believes skincare should be more than a quick task squeezed between two meetings. A few mindful minutes can work wonders—for both your skin and your state of mind. Slow beauty is not just a trend here, it’s a necessity.
Each formula is a luxurious, hand-crafted blend of botanical actives designed to calm, restore and elevate. It’s where traditional Chinese medicine meets aromatherapy, where textures cocoon the skin and scents soothe the soul. Annee de Mamiel doesn’t just create skincare—she creates modern-day healing rituals.
De Mamiel Icons
Restorative Cleansing Balm
This indulgent balm is more than a cleanser—it’s a daily ritual that melts away makeup, tension, and fatigue. The sensorial texture and soothing aroma calm the nervous system while nourishing dry, depleted skin. Ideal for those who crave comfort and reconnection at the end of the day.
First Fix - Stress Response Serum
Thirteen years of R&D went into this pioneering serum that’s become a cult favourite. First Fix addresses stress at every level, working in harmony with your skin’s natural intelligence to repair, balance and protect. Packed with potent botanicals and advanced actives, it’s your skin’s daily reset button.
Skin Recovery Concentrate
Originally created for eczema-prone clients in Annee’s clinic, this comforting blend of healing clays, plant butters, and Cape chamomile acts as a protective cocoon for reactive skin. A balm for dryness, irritation, and moments when your skin needs serious TLC.
Photo credits: De Mamiel
What Clients and Beauty Experts Say About De Mamiel
Curious about how De Mamiel performs in real life? Here's what clients and green beauty insiders have to say:
On the Restorative Cleansing Balm: “This balm is pure joy in a jar. Its scent is divine, and I love taking my time to massage it in. It works beautifully as both a cleanser and makeup remover. The lemony fragrance blooms with a warm cloth, creating a truly relaxing ritual. I don’t use it every day—I like to save it for moments when I can really savour it.” – Anonymous, October 2016
On the Exhale Daily Hydrating Nectar SPF30: “This SPF cream is one of a kind. It’s perfect for everyday city protection—shielding the skin from UV rays and pollution, while its texture smooths the complexion like a soft-focus filter. Yes, it’s pricey, but honestly? Worth every drop. I’ve tried many others, but nothing compares.” – Philo-Sophie, February 2020
From the blog Kleo Beauté: “This balm is the kind of product I live for. It smells heavenly, melts instantly, and the formula? Impeccable. No fillers, no nonsense—just pure, high-grade oils. A luxurious treat I turn to when I need to nourish both my skin and my spirit.” – Read full review
The Glass Magazine on De Mamiel: “For this celebrated acupuncturist and aromatherapist, skincare is more than skin-deep—it’s a gateway to renewal. Her formulas blend organic botanicals and essential oils into transformative rituals that uplift and rebalance. If we had to pick a hero product? The Restorative Cleansing Balm, hands down. It pampers the skin and shields it from urban aggressors with nourishing kukui, calendula, moringa, and antibacterial manuka honey.” – Read full article